Current mechanisms in the pathogenesis of lung fibrosis

Pulmonary fibrosis is a diverse group of lung disorders defined by varying degrees and inflammation in the pulmonary parenchyma. While it may be caused known disease, e.g., autoimmune or connective tissue disorder, drugs, hypersensitivity to inhaled organic antigens, sarcoidosis, also occurs idiopathic. When we examine pathogenesis fibrosis, see that cellular aging plays major role. Lung fibroblasts play an active role regeneration process. However, despite all information, not clearly understood. It yet clear how senescent cells mingle cause fibrosis. The will understood more following future studies.